理化学研究所 生命機能科学研究センター 形態形成シグナル研究チーム(林 研究室)

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研究業績

Original Paper

2000年

Control of tracheal tubulogenesis by Wingless signaling.
Chihara, T. and Hayashi, S
Development. 2000 Oct;127(20):4433-42.

EGF receptor attenuates Dpp signaling and helps to distinguish the wing and leg cell fates in Drosophila
Kubota, K, Goto, S., Eto, K. and Hayashi, S.
Development. 2000 Sep;127(17):3769-76.


1999年

Repression of the wing vein development in Drosophila by the nuclear matrix protein Plexus.
Matakatsu, H., Tadokoro, R., Gamo, S. and Hayashi, S.
Development. 1999 Dec;126(23):5207-16.

Snail-type zinc finger proteins prevent neurogenesis in Scutoid and transgenic animals of Drosophila.
Fuse, N., Matakatsu, H., Taniguchi, M. and Hayashi, S.
Development Genes and Evolution 1999 Oct;209(10):573-80.

Interplay of Notch and FGF signaling restricts cell fate and MAPK activation in the Drosophila trachea.
Ikeya, T. and Hayashi, S.
Development. 1999 Oct;126(20):4455-63.

Proximal to distal cell signaling in the Drosophila leg provides a basis for an intercalary mechanism of limb patterning.
Goto, S. and Hayashi, S.
Development. 1999 Aug;126(15):3407-13.

Kinase-independent activity of Cdc2/cyclin A prevents the S phase in the Drosophila cell cycle.
Hayashi, S. and Yamaguchi, M.
Genes Cells. 1999 Feb;4(2):111-22.


1998年

DNA supercoiling factor localizes to puffs on polytene chromosomes in Drosophila melanogaster.
Kobayashi, M., Aita, N., Hayashi, S., Okada, K., Ohta, T. and Hirose, S.
Molecular and Cellular Biology, November 1998, p. 6737-6744, Vol. 18, No. 11

Interaction between Drosophila EGF receptor and vnd determines three dorsoventral domains of the neuroectoderm.
Yagi, Y., Suzuki, T. and Hayashi, S.
Development. 1998 Sep;125(18):3625-33.

Cell migration within the embryonic limb primordium of Drosophila as revealed by a novel fluorescence method to visualize mRNA and protein.
Goto, S. and Hayashi, S.
Development Genes and Evolution. 207: 194-198


1997年

Role of the Drosophila EGF receptor in determination of the dorsoventral domains of escargot expression during primary neurogenesis.
Yagi, Y. and Hayashi, S.
Genes Cells. 1997 Jan;2(1):41-53.

Specification of the embryonic limb primordium by graded activity of Decapentaplegic.
Goto, S. and Hayashi, S.
Development. 1997 Jan;124(1):125-32.


1996年

Cadherin-mediated cell adhesion and cell motility in Drosophila trachea regulated by the transcription factor Escargot.
Tanaka-Matakatsu, M., Uemura, T., Oda, H., Takeichi, M. and Hayashi, S.
Development. 122: 3697-3705.

Determination of wing cell fate by the escargot and snail genes in Drosophila.
Fuse, N., Hirose, S. and Hayashi, S.
Development. 122: 1059-1067.

A nuclear GFP / β-galactosidase fusion protein as a marker for morphogenesis in living Drosophila.
Shiga, Y., Tanaka-Matakatsu, M. and Hayashi, S.
Development Growth and Differentiation. 38: 99-106.

A Cdc2 dependent checkpoint maintains diploidy in Drosophila.
Hayashi, S.
Development. 122: 1051-1058.

Zygotic DE-cadherin expression is required for processes of dynamic epithelial cell rearrangement in the Drosophila embryo.
Uemura, T., Oda, H., Kraut, R., Hayashi, S., Kataoka, Y. and Takeichi , M.
Genes Dev. 10:659-671.

argos is required for projection of photoreceptor axons during optic lobe development in Drosophila.
Sawamoto, K., Okabe, M., Tanimura, T., Hayashi, S., Mikoshiba, K. and Okano, H.
Developmental Dynamics, 205: 162-171.


1994年

Diploidy of Drosophila imaginal cells is maintained by a transcriptional repressor encoded by escargot.
Fuse, N., Hirose, S. and Hayashi, S.
Genes Dev.8: 2270-2281.

The function of argos in regulating cell fate decisions during the Drosophila eye and wing vein development.
Sawamoto, K., Okano, H., Kobayakawa, Y., Hayashi, S., Mikoshiba, K. and Tanimura, T.
Dev. Biol. 164: 267-276.


1993年

Control of imaginal cell development by the escargot gene of Drosophila.
Hayashi, S., Hirose, S., Metcalfe, T. and Shirras, A.
Development 118: 105-115.


1992年

Regulation of Drosophila neural development by a putative secreted protein.
Okano, H., Hayashi, S., Tanimura,T., Sawamoto, K., Yoshikawa, S., Watanabe, J., Iwasaki, M., Hirose, S., Mikoshiba, K. and Montell, C.
Differentiation 52: 1-11.


1990年

Transcriptional activation by the Antennapedia and fushi tarazu proteins in cultured Drosophila cells.
Winslow, G. M., Hayashi, S., Krasnow, M., Hogness, D. and Scott, M. P.
Cell 57: 1017-1030.

Exogenous d-crystallin gene expression as probe for differentiation of teratocarcinoma stem cells.
Goto, K., Hayashi, S., Shirayoshi, Y., Takeichi, M. and Kondoh, H.
Cell Differentiation 24: 139-148.

Introduction and expression of recombinant b-galactosidase genes in cleavage stage mouse embryos.
Ueno, K., Hiramoto, Y., Hayashi, S. and Kondoh, H.
Develop. Growth and Differ. 30:61-73.

Improved mammalian vectors for high expression of G418 resistance.
Katoh, K., Takahashi, Y., Hayashi, S. and Kondoh, H.
Cell Structure and Function 12: 575-580.

Lens-specific enhancer in the third intron regulates expression of the chicken d-crystallin gene.
Hayashi, S., Goto, K., Okada, T. S. and Kondoh, H.
Genes Dev 1: 818-828.

In vivo competition of d-crystallin expression by DNA fragments containing a GC box.
Hayashi, S. and Kondoh, H.
Mol. Cell. Biol. 6: 4130-4132.

Regulation of the d-crystallin expression:an investigation by transfer of the chicken gene into mouse cells.
Kondoh, H., Hayashi, S., Takahashi, K. and Okada, T.S.
Cell Differentiation 19: 151-160.

Regulation of the d-crystallin expression:an investigation by transfer of the chicken gene into mouse cells.
Kondoh, H., Hayashi, S., Takahashi, K. and Okada, T.S.
Cell Differentiation 19: 151-160.

Tissue-specific regulation of a chicken d-crystallin gene in mouse cells: involvement of the 5’end region.
Hayashi, S., Kondoh, H., Yasuda, K., Soma, G., Ikawa, Y. and Okada, T.S.
EMBO J. 4: 2201-2207.

Two cell division cycle genes NDA2 and NDA3 of fission yeast Schizosaccharomyces pombe control microtubular organization and sensitivity to anti-mitotic benzimidazole compounds.
Umesono, K., Toda, T., Hayashi, S. and Yanagida, M.
J. Mol. Biol. 168: 271-284.